Oral Health Variables and Alzheimer's Disease Continuum
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This journal pre-proof investigates the connection between oral health and the progression of Alzheimer's disease, from early stages of subjective cognitive decline (SCD) through mild cognitive impairment (MCI) to diagnosed Alzheimer's disease (AD). The study recruited older adults and assessed their oral health factors, including tooth loss, occlusal support, and other parameters, alongside cognitive function using standardized tests. Key findings indicate that losing a significant number of natural teeth and reduced occlusal support are associated with increased odds of being in the MCI and AD groups, suggesting that maintaining oral function may be important for cognitive health. Notably, individuals with SCD and poorer occlusal support exhibited lower scores on a specific cognitive assessment, highlighting a potential early marker.
1.Wu, S.-Y. et al. Oral Health Variables Associated with Factors across the Alzheimer’s Disease Continuum: From Subjective Cognitive Decline to Dementia. J. Dent. 105862 (2025) doi:10.1016/j.jdent.2025.105862.
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