Antibiotic therapy in dentistry is crucial for the treatment of bacterial infections. However, it should be used judiciously. Antibiotics should not be prescribed routinely for all dental procedures. They should only be used when necessary and targeted to specific conditions. Clindamycin and amoxicillin are commonly prescribed antibiotics in dentistry. The duration of therapy should be limited and proper patient education is essential. Overall, antibiotic therapy in dentistry plays a vital role in managing infections and preserving oral health.